A single injection of a genetically modified herpes simplex oncolytic virus triggered durable T cell infiltration into brain tumors and was linked to longer survival in a 41-patient phase 1 trial, researchers report in Cell.
A new assessment in One Earth warns cascading climate tipping points could push the planet into irreversible runaway warming, with some ice sheets and ecosystems already showing signs of destabilization.
A University of Colorado Anschutz study shows proteomic and metabolomic markers can forecast organ failure and mortality days in advance, validated in a second cohort and accurate in 92% of cases.
Parliament backed the emergency package 458-140-44 to fund two years of Ukraine’s budget and military needs, with payments expected to begin after European Council sign-off in April.
Northwestern researchers report that levetiracetam stops neurons from making toxic amyloid-beta 42 by altering APP trafficking, based on mouse models, cultured human neurons and brains from people with Down syndrome, study published Feb 11 in Science Translational Medicine.
Researchers report that reducing LETM1 slows mitochondrial calcium efflux about threefold, over-activates neuronal mitochondrial metabolism in memory circuits, and enhances long-term olfactory memory in both Drosophila and mice.
Federal data shows 8.8 million people are at least 270 days behind on federal student loans, with $208 billion in debt in default; the Education Department has paused involuntary collections and plans relief measures starting in July.
Masoud Pezeshkian said he was "ashamed" and pledged support for victims after a brutal security crackdown on nationwide protests that rights groups say left thousands dead.
A meta-meta-analysis of 81 reviews involving nearly 80,000 people shows aerobic, professionally guided and group exercise reduces depression and anxiety, with largest gains for young adults and new mothers.
David Ellison's Paramount Skydance sweetened its $30-per-share hostile offer for Warner Bros. Discovery by adding a 25-cent-per-share quarterly ticking fee after Dec. 31, 2026 and pledging to cover Netflix's $2.8 billion breakup fee, while extending its tender to March 2, 2026.