The Digester

Genomes suggest sharks might not form a single evolutionary group

Mar 17th 2026

A genomic analysis of 48 cartilaginous fishes finds conflicting trees depending on which genomic regions are used, and ultra-conserved DNA regions suggest hexanchiform sharks may sit outside the main shark lineage, which would make most sharks more closely related to rays and skates.

  • Yale researchers Thomas Near and Chase Brownstein compared genomes from 48 sharks, rays and relatives using 840 protein-coding genes and about 350 ultra-conserved regions.
  • Protein-coding genes recover the traditional tree with sharks as a single group separate from rays and skates.
  • Ultra-conserved regions instead place hexanchiforms outside the main shark lineage, implying rays and skates may be nested within sharks and that flat-bodied rays could have evolved from shark-like ancestors.
  • Hexanchiformes include cow sharks and frilled sharks that have six or seven gill slits and primitive jaws, and they form the divergent lineage in the ultra-conserved analysis.
  • The work is a bioRxiv preprint that has not been peer reviewed and the authors say more species sampling and genetic markers are needed to confirm the relationships.