The Digester

10-minute online exercises reduce depression for a month, large trial shows

Mar 6th 2026

A randomized trial published in Nature Human Behaviour found that brief, self-guided interventions under 10 minutes can produce small month-long reductions in depression, with two exercises showing the clearest benefit in a 7,505-person study.

  • Researchers ran a randomized trial with 7,505 US adults testing 12 self-guided single-session interventions that each took under 10 minutes.
  • Two exercises, Interactive Cognitive Reappraisal and Finding Focus, produced small but measurable reductions in depressive symptoms one month later.
  • The average advantage for the two best exercises was about a 4% greater reduction on a standard depression measure versus the control condition.
  • Nearly all interventions boosted immediate feelings of hope and motivation after completion.
  • Interventions ranged from AI-based expressive writing to a program inspired by a Thai ad, and some are available free online, including Koko’s tools.
  • Authors emphasize these single-session programs are not a replacement for therapy but can broaden access and support people who lack other options.