The Digester

Study: US missed about 150,000 COVID deaths in 2020–21

Mar 18th 2026

A Science Advances analysis of CDC records finds about 150,000 to 160,000 likely unrecognized COVID deaths in 2020–21, with the undercount concentrated in marginalized communities.

  • Researchers analyzed 5.7 million CDC death records for adults aged 25 and older from March 2020 through December 2021.
  • A machine learning model trained on hospital deaths identified about 150,000 to 160,000 likely unrecognized COVID deaths on top of 840,251 reported deaths.
  • The estimate implies roughly one overlooked COVID death for every five recorded ones, pushing the two-year U.S. toll close to one million.
  • Unrecognized deaths were more likely among Hispanic people, to occur at home, and to involve people with lower income and less education.
  • Alabama, Oklahoma and South Carolina showed the highest state-level ratios of unrecognized COVID deaths.
  • Authors say fragmented, underresourced death reporting and unequal access to care helped drive the undercount.